Biomedical Data Scientist II

Francesco Tamiro

AI & Biomedical Data Science Architect with deep expertise in single-cell genomics and NGS pipelines. Specialized in translating complex computational analyses into production-grade, AI-first, FAIR-compliant data platforms & infrastructure that democratize advanced bioinformatics for researchers, clinicians, and the broader scientific community. EB-1A (Extraordinary Ability, First Preference) Green Card Holder.

Programming & Tools

Azure

React

Python

Bash

Nextflow

HPC

Git

Data Science & Bioinformatics

Machine Learning

Deep Learning

RNA-seq

ChIP-seq

Cut&Run

ATAC-seq

single-cell RNA-seq

multi-omics single-cell

high throughput flow cytometry

View Portfolio

A History of Consistent Extraordinary Impact

Academic Excellence

Exam Average (Out of 30) vs. National STEM Avg.

Time Efficiency

Years to Degree Completion (Lower is better).

Benchmarked against Almalaurea National Data for Biology cohorts.

Exceptional Efficiency: Completed the Bachelor's degree in 2.75 years, significantly outperforming the national average of 5.1 years for the same cohort (a 46% time reduction).
Accelerated Master's Path: Finished the Master's degree in just 1.73 years (631 days), compared to the national benchmark of 2.7 years (36% faster than the average).
Accelerated Excellence: Demonstrated a consistent ability to navigate complex STEM curricula at approximately twice the speed of the national student population while maintaining top-tier grades. Awarded University Excellence Prize annually for ranking in the top 5% of students and Regional Degree Prize upon graduation.

PhD Funding & Salary Benchmark

Annual gross salary comparison (€).

Publication Impact Factor Benchmarks

Average Impact Factor per publication.

Benchmarked against MUR Decree n. 40/2018, ADI Surveys (2019-2021), Clarivate JCR 2021, ANVUR VQR 2015-2019, and Ministero della Salute 2021 Report.

Competitive PhD Funding: Earned €30,000/year during PhD, 95.5% higher than the national average of €15,343.28. Top 1% of financed research with market value double that of peers.
Publication Impact Excellence: Research output exceeded global/national averages (IF 3.8-4.9), University of Rome Tor Vergata benchmark (IF 5.45), and IRCCS Casa Sollievo della Sofferenza standards (IF 6.81).

Data Science Projects

CLOUD INFRASTRUCTURE • PRODUCTION

Sylvester Data Portal

Leading production pipeline integration across Azure cloud, on-premise, and HPC environments. Specializing in AI integration for research workflows, advanced analytical microservices, and modular tertiary bioinformatics solutions for cancer research.

Azure R Python Bash Nextflow Cromwell React AI Integration

STEALTH • AI AGENTIC

AI Agentic Framework STEALTH

Advanced AI agentic framework for modular tertiary bioinformatic analysis. Automation-first architecture enabling intelligent research workflows and dynamic analytical pipelines.

Python R Bash LangChain OpenAI SDK Shiny

DATA SCIENCE • GENOMICS

Genomic Landscape Analyses

Comprehensive multi-omics data integration and visualization for biomedical research cohorts.

R Python Shiny Jupyter ML ComplexHeatmap

VISUALIZATION • SINGLE-CELL

Single Cell Visualizer

Interactive tool for basic representation of adata objects, designed for quick sharing and collaborative result screening.

Python Streamlit Shiny for Python AnnData Plotly

Selected Publications

NOTCH1 dimeric signaling is essential for T-cell leukemogenesis and leukemia maintenance

Blood

First Author IF: 23.1 2025

The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent anti-inflammatory and antioxidant gene expression

The Journal of Clinical Investigation (JCI)

Middle Author IF: 15.9 2024

Extracellular vesicle microRNAs contribute to Notch signaling pathway in T-cell acute lymphoblastic leukemia

Molecular Cancer

Middle Author IF: 37.3 2022

Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia

Blood

Middle Author IF: 23.1 2021

Targeting leukemia-initiating cells in acute lymphoblastic leukemia

Cancer Research

First Author IF: 16.6 2021

Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

Leukemia

Middle Author IF: 13.4 2024

Microfluidic-enhanced 3D bioprinting of aligned myoblast-laden hydrogels leads to functionally organized myofibers in vitro and in vivo

Biomaterials

Middle Author IF: 15.3 2017 Cited by 364

Personal Projects

MOBILE APP • MUSIC

Absolute PitcheD

A comprehensive training platform for perfect pitch. Built with React Expo for cross-platform availability (Android & Web), featuring advanced performance analytics such as semitone distance tracking for failed guesses.

React Native Expo TypeScript Analytics

DEVOPS • DOCUMENTATION

UOL (Unified Ops Language)

A lightweight, human-first system for standardizing technical procedures. UOL converts free-form notes into structured YAML workflows to generate human-readable manuals and machine-interpretable documentation for AI-assisted automation.

YAML Python Markdown AI/LLM Parsing Git

AI TOOL • CODE ANALYSIS

codeDflow

An LLM-powered tool to reverse-engineer undocumented pipelines. It parses multi-language repositories (Python, R, Bash), uses GPT-4o to resolve cross-file dependencies via context-aware reasoning, and generates structural Graphviz flowcharts.

Streamlit OpenAI SDK Python Graphviz AI/LLM Parsing

STEALTH • AI PSYCHOLOGY

Nosce Te Ipsum STEALTH

AI-driven self-discovery platform integrating SOTA psychological assessments and machine learning to predict compatible friendships, relationships, and collaborators. Features personalized AI journey with life improvement recommendations aligned to your goals and nature.

React Native Expo Machine Learning Psychology AI

Get In Touch

Let's discuss how we can collaborate on exciting bioinformatics projects

Let's Connect

Whether it's optimizing a Nextflow pipeline or designing an end-to-end bioinformatics platform, I enjoy building tools that empower other scientists. Feel free to reach out if you're looking to bridge the gap between raw genomic data and meaningful research insights—I'm always up for a deep dive into the tech.

Contact Me

Feel free to reach out to me directly via email:

francesco.tamiro@gmail.com

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